کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6791292 | 1432685 | 2017 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Impaired contrast sensitivity at low spatial frequency in cannabis users with early onset
ترجمه فارسی عنوان
حساسیت کنترلی ضعف در فرکانس فضایی کم در کاربران کانابیس با شروع زودرس
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کلمات کلیدی
شروع اولیه مصرف شاهدانه، مصرف کمپوست کم کم شروع می شود، حساسیت کنتراست تصویری، فرکانس فضایی کم رانندگی خودرو، توجه
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
The regular use of cannabis generates pronounced cognitive disorders, especially in users who begin before the age of 15-16. However, less is known about the impact of regular cannabis on visual function, especially in the case of early onset. Cannabinoid receptors (CB1) are expressed in areas of the visual system, like the thalamus and primary cortex, which might originate sensory disorders. Hence, we measured contrast sensitivity (CS) in three groups, i.e. cannabis users with late onset of cannabis use (after 16 years old), cannabis users with early onset”. We used a constant method which allowed us to control for biased responses. Stimuli were presented at high and low spatial frequencies and in both static and dynamic conditions (8Â Hz). As contrast sensitivity is measured behaviorally based on an explicit response and could thus be impacted by attentional or vigilance disorders, participants' attention and vigilance were carefully monitored by means of the D2 test, CPT-AX for attention and pupillography for vigilance. Cannabis users with early onset were significantly impaired only at low spatial frequency. This effect was independent of response bias, vigilance and attention. These results show for the first time that early cannabis use impacts contrast sensitivity at low spatial frequency.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Neuropsychopharmacology - Volume 27, Issue 12, December 2017, Pages 1289-1297
Journal: European Neuropsychopharmacology - Volume 27, Issue 12, December 2017, Pages 1289-1297
نویسندگان
Laurence Lalanne, Eglantine Ferrand-Devouge, Sebastien Kirchherr, Lucie Rauch, Estelle Koning, Claude Speeg, Vincent Laprevote, Anne Giersch,