Acid-catalyzed solvent-free synthesis of 2-arylbenzimidazoles under microwave irradiation

2-Arylbenzimidazoles have been synthesized from aromatic carboxylic acid and o-phenylenediamine under microwave irradiation (MW) and solvent-free conditions with catalytic amounts of acid in ambient pressure. This procedure constitutes a simple and practical green synthetic method for benzimidazoles and their structural analogs.

2-Arylbenzimidazoles have been synthesized from aromatic carboxylic acid and o-phenylenediamine under microwave irradiation (MW) and solvent-free conditions with catalytic amounts of hydrochloric acid in ambient pressure. This procedure constitutes a simple and practical green synthetic method for benzimidazoles and their structural analogs. Figure optionsDownload as PowerPoint slide