کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6815057 | 545927 | 2014 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterizing cannabis-induced psychosis: A study with prepulse inhibition of the startle reflex
ترجمه فارسی عنوان
توصیف روانپزشکی ناشی از کانابیس: مطالعه ای با مهار پیشگیری از رفلکس هیجان انگیز
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کلمات کلیدی
اختلال روانپریشی ناشی از کانابیس، جنون جوانی، کانابیس، مهار پیشگیری،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Cannabis-induced psychotic disorder (CIPD) refers to psychotic symptoms that arise in the context of cannabis intoxication. Prepulse inhibition (PPI) deficits have been extensively identified in schizophrenia and in cannabis abusers. We aimed to characterize PPI in CIPD patients. We used a sample of 48 CIPD patients, 54 schizophrenia patients and cannabis abuse (SCHZ), 44 cannabis dependents (CD), and 44 controls. CIPD, SCHZ and CD were abstinent of cannabis consumption for 9 months. Participants were assessed with PPI at 30, 60, and 120Â ms. At 30Â ms, CIPD showed lower PPI levels than controls, and SCHZ obtained worse functioning than controls and CD. At 60Â ms, only SCHZ exhibited worse PPI percentages (of object) than controls. Finally, at 120Â ms, CIPD showed higher PPI levels than SCHZ, and SCHZ obtained lower percentages than controls. We found that CIPD and SCHZ patients showed deficits at the most pre-attentional levels, whereas CIPD patients performed better than SCHZ at higher attentional levels. These results suggest that CIPD constitutes a different group of patients than that of SCHZ. Deficits in PPI functioning at 30Â ms could be a useful psychophysiological measure to detect CIPD patients, who are frequently confused with cannabis abusers whose symptoms may mimic that of schizophrenia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 220, Issues 1â2, 15 December 2014, Pages 535-540
Journal: Psychiatry Research - Volume 220, Issues 1â2, 15 December 2014, Pages 535-540
نویسندگان
Isabel Morales-Muñoz, Rosa Jurado-Barba, Guillermo Ponce, Isabel MartÃnez-Gras, Miguel Ángel Jiménez-Arriero, Stephan Moratti, Gabriel Rubio,