کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6815299 | 545691 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Does substance use disorder affect clinical expression in first-hospitalization patients with schizophrenia? Analysis of a prospective cohort
ترجمه فارسی عنوان
آیا اختلال مصرف مواد در درمان بیماران مبتلا به اسکیزوفرنیا در معرض بیان بالینی قرار دارد؟ تجزیه و تحلیل کوهورت آینده
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کلمات کلیدی
روانپزشکی، سوء مصرف مواد، اختلال مصرف مواد مخدر، اختلالات روان پریشی، بستری شدن مدت اقامت، روانپزشکی ناشی از مواد،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Although several papers reported a wide range of negative outcomes among patients with both schizophrenia and Substance Use Disorder (SUD), only a few studies evaluated the impact of SUD on psychopathology and thus on the length of first-hospitalization. The aim of the present study was to compare clinical expression of first-episode of schizophrenia between inpatients with and without SUD, giving close attention to the length of stay. One hundred and thirty inpatients at first-episode of schizophrenia were assigned to either SUD or not SUD group depending on SUD diagnosis and were assessed through BPRS at admission, during hospitalization and at discharge. Cross-sectional and longitudinal statistical analysis were performed to investigate differences between groups and also a linear regression was used to evaluate relationship between length of stay and BPRS scores. SUD group showed more disorganization at admission, less marked improvement of symptoms (disorganization, thought disturbance, anergia), and longer hospital stay than not SUD group. Moreover BPRS total score during hospitalization was a significant positive predictor for length of stay. Taken together, these findings suggest that SUD patients have a more severe and drug-resistant expression of schizophrenia, hence, they need longer treatment to achieve the overall symptoms improvement required for discharge.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 210, Issue 3, 30 December 2013, Pages 780-786
Journal: Psychiatry Research - Volume 210, Issue 3, 30 December 2013, Pages 780-786
نویسندگان
Rocco Luigi Picci, Elisabetta Versino, Francesco Oliva, Roberta Margherita Giaretto, Luca Ostacoli, Federica Trivelli, Sara Venturello, Pier Maria Furlan,