Cognitive course in first-episode psychosis and clinical correlates: A 4Â year longitudinal study using the MATRICS Consensus Cognitive Battery

In conclusion, an initial psychotic episode may be associated with an additional cost on verbal learning and two measures of processing speed over a time spanning at least four years. Moreover, processing speed, which has been manipulated through intervention in previous studies, may represent a viable therapeutic target. Finally, cognition at illness onset may have a predictive capability of illness course.