Chiral cationic diamidophosphite: Novel effective ligand for Pd-catalysed enantioselective allylic substitution

Novel diamidophosphite ligand bearing alkylammomium fragment was prepared by a one-step phosphorylation of a quaternised aminoalcohol. The ionic ligand demonstrated high enantioselectivity in the Pd-catalysed allylic substitution of 1,3-diphenylallyl acetate (up to 99% ee)