Study of conventional versus microwave-assisted reactions of 3,4-epoxyalcohols by CeCl3·7H2O: Synthesis of tetrahydrofurans and 1-chloro-3-substituted-2-propanols

3,4-Epoxyalcohols undergo regioselective cyclization in the presence of CeCl3·7H2O in ref1uxing acetonitrile to afford tetrahydrofuran derivatives in good yields. On the other hand epoxyalcohols afforded 1-chloro-3-substituted-2-propanols under microwave irradiation using CeCl3·7H2O supported on SiO2 under solvent-free conditions.

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