Solventless and swift benzoin condensation catalyzed by 1-alkyl-3-methylimidazolium ionic liquids under microwave irradiation

A solventless benzoin condensation was performed with several imidazolium-based ionic liquids as catalysts under microwave irradiation. The process enables the formation of α-hydroxy-α-phenylacetophenone with good yield (up to 97%) and purity in a very short time. Moreover, the work-up only requires the use of water, giving a green touch to the overall process.

An eco-friendly solventless and quick benzoin condensation is reported. Different 1-alkyl-3-methyl-imidazolium based ionic liquids are used as catalysts of a reaction activated by microwave irradiation. In these conditions, up to 97% yield are obtained for a 5-min reaction time. Figure optionsDownload as PowerPoint slide