Gallium(III) iodide-promoted stereoselective aldol coupling of α,β-acetylenic ketones

A simple and highly stereoselective method has been developed for the synthesis of (Z)-β-iodo Baylis–Hillman adducts utilizing gallium(III) iodide as a novel reagent. This new procedure offers significant advantages such as high conversions, short reaction times and enhanced Z-selectivity together with mild reaction conditions.

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