کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
68983 | 48527 | 2006 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: ZrOCl2·8H2O as a highly efficient and the moisture tolerant Lewis acid catalyst for Michael addition of amines and indoles to α, β-unsaturated ketones under solvent-free conditions ZrOCl2·8H2O as a highly efficient and the moisture tolerant Lewis acid catalyst for Michael addition of amines and indoles to α, β-unsaturated ketones under solvent-free conditions](/preview/png/68983.png)
The 1,4-conjugate addition of indoles and amines to cyclic and acyclic α, β-unsaturated ketones for C–N bond formation was efficiently carried out under solvent-free conditions at 50 °C using a catalytic amount of ZrOCl2·8H2O as a moisture tolerant Lewis acid. The reusability of the catalyst has been successfully examined without noticeable loss of its catalytic activity.
ZrOCl2·8H2O as a safe, inexpensive, air and moisture tolerant Lewis acid catalyst were used for efficient Michael addition of indoles and amines to cyclic and acyclic α, β-unsaturated ketones under solvent-free conditions at 50 °C without any side reactions. The catalyst successfully reused several times for next round of reactions. Figure optionsDownload high-quality image (34 K)Download as PowerPoint slide
Journal: Journal of Molecular Catalysis A: Chemical - Volume 252, Issues 1–2, 1 June 2006, Pages 150–155