Kinetic study for benzyloxylation of p-bromotoluene using phase transfer catalyst assisted by microwave irradiation

• Phase-transfer catalysis assisted by microwave irradiation.
• A reaction of benzyloxylation.
• Application of pseudo-first order rate equation.
• Nucleophilic substitution reaction.
• Enhanced rate of the reaction to synthesize.

The synthesis of 4-benzyloxy toluene was successfully carried out by reacting the sodium benzyloxide (BnO−Na+) with p-bromotoluene and sodium hydroxide/phase transfer catalyst system at 50 °C under microwave irradiation. The nucleophilic susbstitution reaction was well explained by comparing the phase transfer catalyst system and microwave irradiation. The chemical kinetics of the reaction depends on the amount of catalyst, amount of sodium hydroxide, effect of phase-transfer catalysts, volume of benzylalcohol (BnOH) and temperature on the transformation of the reaction were studied.

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