Application of non-imidazolium-based ionic liquid in the Baylis–Hillman reactions: Rate and yield promoted

The application of non-imidazolium-based ionic liquid [EtPy][BF4] (N-1-ethylpyridinium tetrafluoraborate) as recyclable solvent for the Baylis–Hillman reactions was presented. Compared with the commonly used imidazolium-based ionic liquid [bmim][PF6] (1-n-butyl-3-methylimidazolium hexafluorophosphate) and [bdmim][PF6] (1-n-butyl-2,3-dimethylimidazolium hexafluorophosphate) that evidently reacts with aldehydes under basic conditions, ionic liquid [EtPy][BF4] is inert and the Baylis–Hillman reactions in [EtPy][BF4] proceed quickly with good yields.

The application of non-imidazolium-based ionic liquid [EtPy][BF4] (N-1-ethylpyridinium tetrafluoraborate) as recyclable solvent for the Baylis–Hillman reactions is presented. Compared with the commonly used imidazolium-based ionic liquid [bmim][PF6] (1-n-butyl-3-methylimidazolium hexafluorophosphate) and [bdmim][PF6] (1-n-butyl-2,3-dimethyl-imidazolium hexafluorophosphate) that evidently reacts with aldehydes under basic conditions, ionic liquid [EtPy][BF4] is inert and the Baylis–Hillman reaction in [EtPy][BF4] proceeds quickly with good yields. Figure optionsDownload as PowerPoint slide