کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
69219 | 48533 | 2006 | 8 صفحه PDF | دانلود رایگان |
Alkylation of guaiacol(2-methoxyphenol) with cyclohexene gives both O- and C-alkylated products. The O-alkylated product 1-cyclohexyloxy-2-methoxybenzene(cyclohexyl-2-methoxyphenyl ether) is used as a perfumery compound. The current work was aimed at achieving maximum selectivity for this product by using an active catalyst with minimum separation cost. It covers the use of a variety of solid acid catalysts such as sulphated zirconia, Amberlyst-15, Filtrol-24, Indion-130, 20% (w/w) dodecatungstophosphoric acid supported on K-10 clay (DTP/K-10) and 20% (w/w) cesium-modified dodecatungstophosphoric acid supported over K-10 clay (Cs2.5H0.5PW12O40/K-10). Sulphated zirconia was found to be the best catalyst to achieve maximum selectivity for the ether. The O-alkylation versus C-alkylation selectivity was not only highly temperature sensitive but also the pore size and nature of acidic sites also played an important role. The reaction was carried out without using solvent. No oligomerisation of cyclohexene was formed over the temperature range employed. A suitable kinetic model is proposed and validated.
Sulphated zirconia is used to promote etherification of guaicol with cyclohexene very effectively. Figure optionsDownload as PowerPoint slide
Journal: Journal of Molecular Catalysis A: Chemical - Volume 243, Issue 1, 2 January 2006, Pages 77–84