Redox/pH stimuli-responsive biodegradable PEGylated P(MAA/BACy) nanohydrogels for controlled releasing of anticancer drugs

- A new kind of redox/pH dual stimuli-responsive biodegradable PEGlated nanohydrogels.
- The PEGlated nanohydrogels could be degraded into short linear polymer chains in tumor cells.
- The hydrophilic nanohydrogels could simultaneously load hydrophilic drug doxorubicin (DOX) and hydrophobic drug paclitaxel (PTX).
- This novel multi-drug-loaded system had synergistic effect on cancer therapy.