Response of osteoblasts and preosteoblasts to calcium deficient and Si substituted hydroxyapatites treated at different temperatures

- Scaffolds of CDHA and SiHA treated at either 1250 °C or 700 °C were evaluated for bone cell growth.
- Higher cell proliferation and differentiation were observed on 1250 °C CDHA and SiHA scaffolds.
- Lower albumin and fibrinogen adsorption and better mechanical properties in 1250 °C CDHA and SiHA scaffolds.
- Bone cells prefer 1250 °C CDHA and SiHA scaffolds.