Peptide-laden mesoporous silica nanoparticles with promoted bioactivity and osteo-differentiation ability for bone tissue engineering

- An innovative p-MSNs are synthesized to slow-release peptide osteogenic factor.
- The p-MSNs induce the adhesion and proliferation of MG-63 cells.
- The osteo-differentiation of the p-MSNs is enhanced after decoration of peptide.
- Combination of MSNs and growth factors presents a potential for tissue engineering.