Nano-anisotropic surface coating based on drug immobilized pendant polymer to suppress macrophage adhesion response

- Surface coating with combined physical and biological properties was developed.
- The drug, as a pendant produces physical properties and as ligand produces biological functions.
- .The physical properties are roughness, coating stability and thermoresponsiveness.
- The biological function is due to ligand--receptor interaction between drug and the albumin.
- The self-adhesive surface coating suppresses macrophage adhesion responses.