Synthesis, characterization and toxicological evaluation of iron oxide nanoparticles in human lung alveolar epithelial cells

- Fe3O4-NPs were synthesized by chemical co-precipitation methods.
- Fe3O4-NPs were characterized by XRD, TEM, DLS, and AFM.
- Fe3O4-NPs induced a concentration-dependent cytotoxicity in A-549 cells.
- Fe3O4-NPs induced oxidative stress and ROS generation in A-549 cells.
- Fe3O4-NPs decreased the mitochondrial membrane potential in A-549 cells.