Indole conjugated silica and magnetic nanoparticles as inhibitors of HIF

- Indole conjugated nanosilica and magnetic nanoparticles were constructed.
- Indole conjugated magnetic nanoparticles are found to be good mimics of catalase.
- The time dependent cytoxicity of magnetic nanoparticles is reported.
- The two nanoparticles can inhibit the expression of HIF and GLUT1 in vitro.
- A new way to construct inhibitor of glycolysis is reported.