Rapid synthesis of propyl caffeate in ionic liquid using a packed bed enzyme microreactor under continuous-flow conditions

- A packed bed enzyme microreactor was firstly used for the rapid synthesis of propyl caffeate.
- The enzymatic reaction parameters under continuous-flow conditions were optimized.
- The maximum yield of propyl caffeate (99.5%) was achieved in a short time (2.5 h).
- Km in the developed microreactor was 16 times lower than that of a batch reactor.