Improved production of butyl butyrate with lipase from Thermomyces lanuginosus immobilized on styrene-divinylbenzene beads

► TLL was immobilized on styrene-divinylbenzene beads (MCI-TLL). ► MCI-TLL was compared to Lipozyme TL-IM in butyl butyrate synthesis. ► MCI-TLL presented two-times more protein than Lipozyme TL-IM. ► The prepared biocatalyst was stable to higher concentration of butyric acid. ► MCI-TLL showed productivity 4-times higher than Lipozyme TL-IM.