Responses of Synechocystis sp. PCC 6803 to total dissolved solids in long-term continuous operation of a photobioreactor

- The growth of Synechocystis sp. PCC 6803 was inhibited by high-TDS stress.
- The high TDS was due to addition of inorganic C and N as nutrients.
- High TDS led to higher Ci, lower pH, and HCO3− dominance.
- TDS stress from HCO3−and NO3− differed from stress from Na+ and Cl−.