Novel magnetic cross-linked enzyme aggregates (magnetic CLEAs) of alpha amylase

► Novel method of preparation of magnetic CLEAs of alpha amylase was developed. ► Enzyme was cross linked with amino functionalized magnetite nanoparticles. ► Amino functionalized magnetite nanoparticles enhanced cross linking efficiency. ► Magnetic CLEAs could be separated from reaction mixture by magnetic field. ► Magnetic CLEAs enhanced stability and reusability of enzyme.