Fractionation of wheat straw by prehydrolysis, organosolv delignification and enzymatic hydrolysis for production of sugars and lignin

► Wheat straw fractionation by prehydrolysis prior to organosolv delignification. ► Prehydrolysis-organosolv compared to direct organosolv fractionation. ► Prehydrolysis improves yield of xylose by avoiding degradation during organosolv. ► Prehydrolysis improves enzymatic glucose yield after organosolv delignification.