Fe3O4@mZnO nanoparticles as magnetic and microwave responsive drug carriers

• Fe3O4@mZnO nanoparticles have been fabricated by template-free method.
• The nanoparticles have magnetic and microwave to heat responsive properties.
• The nanoparticles are feasibly applicable to drug delivery and thermal therapy.

Mesoporous and core–shell structure nanomaterials have attracted great attention owing to their unique characteristics and promising applications in drug delivery, and water treatment. In this paper, Fe3O4@mZnO (m was short for mesoporous) core–shell structured nanoparticles with magnetic, microwave to heat responsive properties and high specific surface area (93 m2 g−1) were synthesized by a simple template-free homogeneous precipitation method. The nanoparticles not only has the large accessible pore size (6.7 nm) for the physical adsorption of drug molecules and showed both strong magnetic and unique microwave to heat responsive properties, which may lead to development of nanoparticles with great potential for applications in drug targeting, chemo- and microwave-thermal combination therapy and water treatment.

We developed a facile synthesis route to prepared Fe3O4@mZnO nanoparticles. It has both strong magnetic and unique microwave to heat responsive properties. The nanoparticles are feasibly applicable to simultaneous target drug delivery and microwave-thermal therapy.Figure optionsDownload as PowerPoint slide