Multifunctional microelectrode array (mMEA) chip for neural-electrical and neural-chemical interfaces: Characterization of comb interdigitated electrode towards dopamine detection

► An integrated multifunctional microelectrode array chip was successfully demonstrated. ► Dopamine sensor modality fabricated in interdigitated electrodes fashion was comprehended. ► Chip was applied to trace dopamine exocytosis from PC12 cells. ► Collection efficiency and amplification effect of the IDE were systematically evaluated.