Multimodal doxorubicin loaded magnetic nanoparticles for VEGF targeted theranostics of breast cancer

Targeted therapy is one of the most advanced techniques in treatment of malignant tumors, but still it has some limitations, mostly associated with difficulties in development and clinical approbation of new tumor specific ligands. One of the approaches is to use already existing molecules as targeting moieties. In this study we present use of monoclonal antibodies to VEGF as effective ligand for doxorubicin loaded magnetic nanoparticles delivery for tumor therapy and diagnostics.89