Hydrothermal synthesis of anatase titanium dioxide mesoporous microspheres and their antimicrobial activity

• Anatase TiO2 mesoporous microspheres was synthesized by a facile hydrothermal method.
• The microspheres showed high surface area of 283 m2 g−1.
• Dopant Fe was incorporated in the mesoporous microspheres.
• The Fe doped microspheres exhibited improved antimicrobial activity.

We report here the synthesis of high surface area mesoporous microspheres of anatase titanium dioxide via nanoparticle assembly in a simple one pot hydrothermal reaction. The same procedure is applied to synthesize Fe-doped titanium dioxide mesoporous microspheres. The surface areas of the microspheres are as high as 283 m2 g−1. The antimicrobial activity of these microspheres is investigated against a broad range of Gram-negative and Gram-positive bacteria. The Fe-doped titanium dioxide microspheres exhibited improved antimicrobial activity against Mycobacterium smegmatis, Klebsiella pneumoniae, Staphylococcus aureus and Bacillus subtilis.

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