کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7295458 1474409 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adolescent earthquake survivors' show increased prefrontal cortex activation to masked earthquake images as adults
ترجمه فارسی عنوان
نمایشگاه بازماندگان نوجوان زلزله، فعال شدن قشر پرهفرنات را به تصاویر زلزله های ماسک به عنوان بزرگسالان افزایش داد
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
The great Sichuan earthquake in China on May 12, 2008 was a traumatic event to many who live near the earthquake area. However, at present, there are few studies that explore the long-term impact of the adolescent trauma exposure on adults' brain function. In the present study, we used functional magnetic resonance imaging (fMRI) to investigate the brain activation evoked by masked trauma-related stimuli (earthquake versus neutral images) in 14 adults who lived near the epicenter of the great Sichuan earthquake when they were adolescents (trauma-exposed group) and 14 adults who lived farther from the epicenter of the earthquake when they were adolescents (control group). Compared with the control group, the trauma-exposed group showed significant elevation of activation in the right anterior cingulate cortex (ACC) and the medial prefrontal cortex (MPFC) in response to masked earthquake-related images. In the trauma-exposed group, the right ACC activation was negatively correlated with the frequency of symptoms of post-traumatic stress disorder (PTSD). These findings differ markedly from the long-term effects of trauma exposure in adults. This suggests that trauma exposure during adolescence may have a unique long-term impact on ACC/MPFC function, top-down modulation of trauma-related information, and subsequent symptoms of PTSD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Psychophysiology - Volume 95, Issue 3, March 2015, Pages 292-298
نویسندگان
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