کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7303104 1475302 2016 64 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Alterations in emotion generation and regulation neurocircuitry in depression and eating disorders: A comparative review of structural and functional neuroimaging studies
ترجمه فارسی عنوان
تغییرات در ساخت و ساز عروق خلقی و تنظیم کننده نوروپروتئین در افسردگی و اختلالات خوردن: یک مقایسه تطبیقی ​​از مطالعات ساختاری و عملکردی تصویربرداری عصبی
کلمات کلیدی
افسردگی، اختلالات اشتها، هیجانی، مقررات احساسی، تصویر برداری عصبی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
Major depression and eating disorders (EDs) are highly co-morbid and may share liability. Impaired emotion regulation may represent a common etiological or maintaining mechanism. Research has demonstrated that depressed individuals and individuals with EDs exhibit impaired emotion regulation, with these impairments being associated with changes in brain structure and function. The goal of this review was to evaluate findings from neuroimaging studies of depression and EDs to determine whether there are overlapping alterations in the brain regions known to be involved in emotion regulation, evidence of which would aid in the diagnosis and treatment of these conditions. Our review of the literature suggests that depression and EDs exhibit common structural and functional alterations in brain regions involved in emotion regulation, including the amygdala, ventral striatum and nucleus accumbens, anterior cingulate cortex, insula, and dorsolateral prefrontal cortex. We present preliminary support for a shared etiological mechanism. Future studies should consider manipulating emotion regulation in a sample of individuals with depression and EDs to better characterize abnormalities in these brain circuits.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience & Biobehavioral Reviews - Volume 68, September 2016, Pages 911-927
نویسندگان
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