Magnetic cylindrical ordered mesoporous nanocarriers for targeted drug delivery

• Synthesis cylindrical ordered-mesoporous silicon dioxide magnetic nanocarrier by double surfactant system.
• Use infrared excitation fluorescent dye to demonstrate cells uptake process.
• Use the nano-material load doxorubicin and get a nice drug release curve.
• In vivo experiment show the material can be independently metabolized.

An MCM-41 type magnetic cylindrical ordered mesoporous silicon dioxide (M-COMSD) nanocarrier for targeted drug delivery has been synthesised. Pharmaceutical drug molecules have been loaded into the mesoporous framework of the M-COMSD. In vitro (Hale cells) and in vivo (mice) drug storage and release experiments of the nanocarrier have been performed. The results of the M-COMSD system demonstrate that this material could play a significant role in developing a new generation of controlled-release nanocarriers.

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