کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
73504 | 49062 | 2013 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Facile synthesis of PDMAEMA-coated hollow mesoporous silica nanoparticles and their pH-responsive controlled release Facile synthesis of PDMAEMA-coated hollow mesoporous silica nanoparticles and their pH-responsive controlled release](/preview/png/73504.png)
A versatile method of grafting poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) on the surface of hollow mesoporous silica nanoparticles (HMSN) via surface-initiated atom transfer radical polymerization (SI-ATRP) has been presented. TEM, FT-IR, TGA, XRD, and N2 adsorption–desorption analysis were used for the characterization. The results state that the stimuli-responsive polymer has been successfully grafted onto the surface of HMSN. These hybrid nanoparticles have been proven to have a large storage capacity which can be applied in drug delivery. The external coated PDMAEMA layers act as a storage gate as well as a release switch in response to the stimuli of environment. In this paper, pH-responsive controlled release behavior was focused.
.Figure optionsDownload as PowerPoint slideHighlights
► Facile strategy for grafting PDMAEMA on the surface of HMSN.
► The responsive polymer brushes can act as a switch to control the opening and closing of the mesopores.
► Modified HMSN can have potential applications in drug delivery systems.
Journal: Microporous and Mesoporous Materials - Volume 173, June 2013, Pages 64–69