کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
74400 | 49090 | 2011 | 9 صفحه PDF | دانلود رایگان |

The zirconium (Zr) containing mesoporous bioactive glasses (MBGs) scaffolds with different Zr contents have been prepared by the combination of polyurethane sponge and P123 surfactant as co-templates and evaporation-induced self-assembly (EISA) process using Ca, P, Si and Zr sources. The study showed that the Zr incorporation in the MBGs scaffolds enhanced the compressive strength, decreased the dissolution, maintained a more stable pH environment, and kept the apatite formation ability. Furthermore, the Zr incorporation provided a better environment for BMSCs attachment, spreading and proliferation on these MBGs scaffolds. Therefore, the Zr incorporated MBGs scaffolds have more potential for use in bone tissue engineering application.
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► The Zr incorporated mesoporous bioactive glasses (MBGs) scaffolds were synthesized.
► The Zr incorporation enhanced the compressive strength of the MBGs scaffolds.
► The Zr incorporation kept the apatite formation ability of the MBGs scaffolds.
► The Zr incorporation facilitated BMSCs attachment, spreading and proliferation.
► The Zr incorporated MBGs scaffolds exhibited a sustained drug release property.
Journal: Microporous and Mesoporous Materials - Volume 143, Issues 2–3, September 2011, Pages 311–319