Expert voices for change: Bridging the silos-towards healthy and sustainable settings for the 21st century

► The settings approach has to varying extents been embedded in cross-sectoral policy and practice. ► Healthy Cities offers an infrastructure to connect settings, but these tend to remain siloed. ► The settings approach is determinants-focussed and can integrate effective advocacy for change. ► We must reconfigure the settings approach to ensure relevance to complex 21st century challenges. ► This requires us to maximise synergy between settings and with agendas such as sustainability.