Mesoporous silica modified with enantiopure sulfoxide as catalyst in allylation of aldehydes

Enantiopure sulfoxides prepared via biooxidation with engineered yeast (Saccharomyces cerevisiae) and E. coli overexpressing enzyme cyclohexanone monooxygenase (CHMO) were used as chiral liners for mesoporous silica SBA-15. The protocols for attachment of these chiral groups to the cavities of the silicates are described. The SBA-15 with grafted chiral sulfoxide was evaluated as a solid catalyst for asymmetric allylation.