Preparation and Evaluation of a C18-Sulfonic Group Dual Modification Chromatographic Stationary Phase

A C18-sulfonic group dual modification chromatographic stationary phase was prepared with two modifier of octadecyltrichlorosilane (OTS) and trimethoxysilylpropanethiol (MPS). The morphology and feature of the stationary phase were characterized by SEM, elemental analysis and IR spectra. The chromatographic properties of the prepared stationary phase were systematically investigated in different separation mode.