کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7584551 | 1492026 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Study on the apoptosis mediated by apoptosis-inducing-factor and influencing factors of bovine muscle during postmortem aging
ترجمه فارسی عنوان
بررسی آپوپتوز به وسیله عوامل ایجاد کننده آپوپتوز و عوامل موثر بر عضله گاو در طی زایمان بعد از زایمان
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
This study investigated the apoptosis pathway mediated by apoptosis-inducing factors (AIF) and internal factors that influence the release of AIF. The results indicated that the AIF expression was decreased in mitochondria and increased in nucleus (Pâ¯<â¯0.05). However, no significant differences were observed in the AIF expression in mitochondria with caspase inhibitor treatment. The optical density of nucleus and mitochondrial swelling was significant increased (Pâ¯<â¯0.05). Reactive oxygen species (ROS) fell gradually within the first 6â¯h and increased in the next 24â¯h. Calpain I activity was decreased, Ca2+ concentration, cathepsin B and D activities was increased (Pâ¯<â¯0.05). The results demonstrated that AIF-mediated caspase-dependent pathway was a new mitochondrial apoptosis pathway and that mitochondrial swelling, ROS content, Ca2+ concentration, calpain I, cathepsin B and cathepsin D activities are the key influencing factors in apoptosis in postmortem bovine muscle.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 266, 15 November 2018, Pages 359-367
Journal: Food Chemistry - Volume 266, 15 November 2018, Pages 359-367
نویسندگان
Jiaying Zhang, Guoyuan Ma, Zhaobin Guo, Qunli Yu, Ling Han, Mingshan Han, Yueming Zhu,