کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7590024 | 1492099 | 2016 | 42 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A novel chemo-enzymatic synthesis of hydrophilic phytosterol derivatives
ترجمه فارسی عنوان
سنتز شیمیایی آنزیمی جدید از مشتقات فیتواسترول هیدروفیلی
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کلمات کلیدی
فیتوسترولها، آب دوست، پلی اتیلن گلیکول، لیپاز، استرینگ،
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
In this study, a novel method was developed for chemo-enzymatic synthesis of hydrophilic phytosterol derivatives, phytosteryl polyethylene glycol succinate (PPGS), through an intermediate phytosteryl hemisuccinate (PSHS), which was first chemically prepared and subsequently coupled with polyethylene glycol (PEG) through lipase-catalyzed esterification. The chemical structure of intermediate and goal product were finally confirmed to be PSHS and PPGS by FT-IR, MS and NMR, suggesting that hydrophilic phytosterol derivatives were successfully synthesized. The effects of various parameters on the conversion of PSHS to PPGS were investigated and the highest conversion (>78%) was obtained under the selected conditions: 75Â mmol/L PSHS, 1:2Â M ratio of PSHS to PEG, 50Â g/L Novozym 435, 120Â g/L 3Â Ã
molecular sieves in tert-butanol, 55 °C, 96 h and 200 rpm. The solubility of phytosterols in water was significantly improved by coupling with PEG, facilitating the incorporation into a variety of foods containing water.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 192, 1 February 2016, Pages 557-565
Journal: Food Chemistry - Volume 192, 1 February 2016, Pages 557-565
نویسندگان
Wen-Sen He, Di Hu, Yu Wang, Xue-Yan Chen, Cheng-Sheng Jia, Hai-Le Ma, Biao Feng,