کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7595428 | 1492123 | 2015 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The pecan nut (Carya illinoinensis) and its oil and polyphenolic fractions differentially modulate lipid metabolism and the antioxidant enzyme activities in rats fed high-fat diets
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Tree nuts such as pecans (Carya illinoinensis) contain mostly oil but are also a source of polyphenols. Nut consumption has been linked to a reduction in serum lipid levels and oxidative stress. These effects have been attributed to the oil while overlooking the potential contribution of the polyphenols. Because the evidence regarding each fraction's bioactivity is scarce, we administered high-fat (HF) diets to male Wistar rats, supplementing them with pecan oil (HFÂ +Â PO), pecan polyphenols (HFÂ +Â PP) or whole pecans (HFÂ +Â WP), and analysed the effects of each fraction. The HF diet increased the serum leptin and total cholesterol (TC) with respect to the control levels. The HFÂ +Â WP diet prevented hyperleptinemia and decreased the TC compared with the control. The HFÂ +Â WP diet upregulated the hepatic expression of apolipoprotein B and LDL receptor mRNAs with respect to the HF levels. The HFÂ +Â PO diet reduced the level of triacylglycerols compared with the control. The HFÂ +Â PP diet stimulated the hepatic expression of liver X receptor alpha mRNA. The HFÂ +Â WP diet increased the activities of hepatic catalase, glutathione peroxidase and glutathione S transferase compared with the control, and decreased the degree of lipid peroxidation compared with the HF diet. The most bioactive diet was the WP diet.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 168, 1 February 2015, Pages 529-537
Journal: Food Chemistry - Volume 168, 1 February 2015, Pages 529-537
نویسندگان
Jesús A. DomÃnguez-Avila, Emilio Alvarez-Parrilla, José A. López-DÃaz, Ignacio E. Maldonado-Mendoza, MarÃa del Consuelo Gómez-GarcÃa, Laura A. de la Rosa,