کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7600893 | 1492146 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Increased stability and protease resistance of the β-lactoglobulin/vitamin D3 complex
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
The stability of the β-lactoglobulin (βlg)/vitamin D3 (D3) complex at 4 °C and upon exposure to UV-C light, and in simulated intestinal fluid, were studied in vitro. Caco-2 cells were used to demonstrate the passage of the βlg/D3 complex across the monolayers. Furthermore, an in vivo experiment was conducted by force-feeding rats with the free D3 and βlg/D3 complex, with subsequent determination of the plasma concentration of 25-hydroxy-D3. The βlg/D3 complex significantly improved the stability of the vitamin at 4 °C and when exposed to UV-C light. The resistance of βlg to proteases was increased, indicating a mutual protective effect. The βlg/D3 complex crossed the monolayers, which was confirmed by the significant increase in the concentration of 25-hydroxy-D3 in rats fed the βlg/D3 complex compared to the ones fed the free D3. Therefore, the current study suggests that the βlg/D3 complex can effectively be used for the fortification of milk products and low-fat content foods to improve the intake and bioavailability of D3.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 145, 15 February 2014, Pages 646-652
Journal: Food Chemistry - Volume 145, 15 February 2014, Pages 646-652
نویسندگان
Fatoumata Diarrassouba, Ghislain Garrait, Gabriel Remondetto, Pedro Alvarez, Eric Beyssac, Muriel Subirade,