Root tubers of Lactuca tuberosa as a source of antioxidant phenolic compounds and new furofuran lignans

► This is the first report on chemical constituents of Lactuca tuberosa. ► From root tubers nine phenolic compounds were isolated. ► Two new furofuran lignan glucosides were characterised. ► Quantification of caffeic acid and its derivatives was performed. ► Total phenolic content and radical scavenging activity were evaluated.