Isolation and antimutagenic activity of some flavanone compounds from Kaempferia rotunda

From the dried and milled rhizoma of K. rotunda, three known flavanones, namely 5-hydroxy-7-methoxyflavanone (1), 7-hydroxy-5-methoxyflavanone (2), and 5,7-dihydroxyflavanone (3) were isolated. The methanol extract and isolated flavanones from K. rotunda showed significant antimutagenic effect compared to control group.