کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7609496 | 1493400 | 2017 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Estimation of descriptors for hydrogen-bonding compounds from chromatographic and liquid-liquid partition measurements
ترجمه فارسی عنوان
ارزیابی توصیفگرهای ترکیبات هیدروژن اتصال از اندازه گیری های پراکندگی کروماتوگرافی و مایع
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Retention factors obtained by gas chromatography and reversed-phase liquid chromatography on varied columns and partition constants in different liquid-liquid partition systems are used to estimate WSU descriptor values for 36 anilines and N-heterocyclic compounds, 13 amides and related compounds, and 45 phenols and alcohols. These compounds are suitable for use as calibration compounds to characterize separation systems covering the descriptor space EÂ =Â 0.2-3, SÂ =Â 0.4-2.1, AÂ =Â 0-1.5, BÂ =Â 0.1-1.5, LÂ =Â 2.5-10.0 and VÂ =Â 0.5-2.2. Hydrogen-bonding properties are discussed in terms of structure, the possibility of induction effects, intramolecular hydrogen bonding and steric factors for anilines, amides, phenols and alcohols. The relationship between these parameters and observed descriptor values are difficult to predict from structure but facilitate improving the general occupancy of the descriptor space by creating incremental changes in hydrogen-bonding properties. It is verified that the compounds included in this study can be merged with an existing database of compounds recommended for characterizing separation systems.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1526, 1 December 2017, Pages 13-22
Journal: Journal of Chromatography A - Volume 1526, 1 December 2017, Pages 13-22
نویسندگان
Nicole Lenca, Sanka N. Atapattu, Colin F. Poole,