کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7611406 1493512 2015 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development and validation of a stable-isotope dilution liquid chromatography-tandem mass spectrometry method for the determination of bisphenols in ready-made meals
ترجمه فارسی عنوان
توسعه و اعتبار سنجی طیف سنجی جرم کروماتوگرافی مایع رقیق شده با ایزوتوپ پایدار برای تعیین بیسفنول در وعده های آماده شده
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Extraction was carried out by ultrasound-assisted extraction after sample disruption with sand. A selective solid-phase extraction procedure was then applied to reduce potential matrix interferences. Derivatization of bisphenols with pyridine-3-sulfonyl chloride increased their ionization efficiency by electrospray ionization. Validation of the proposed method was performed in terms of selectivity, matrix effects, linearity, precision, measurement uncertainty, trueness and limits of detection. Satisfactory repeatability and intermediate precision were obtained; the related relative standard deviations were ≤7.8% and ≤10%, respectively. The relative expanded uncertainty (k = 2) was below 17% for all bisphenol analogs and the trueness of the method was demonstrated by spike recovery experiments. Low limits of detection, in the range from 0.025 μg kg−1 to 0.140 μg kg−1, were obtained for all compounds. To demonstrate the applicability of the proposed method, it was eventually applied to several ready-made meals purchased from different supermarkets in Belgium.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1414, 2 October 2015, Pages 110-121
نویسندگان
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