کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7613474 1493588 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chromatographic behavior of new antiepileptic active compounds on different reversed-phase materials
ترجمه فارسی عنوان
رفتار کروماتوگرافی ترکیبات فعال ضد عفونی جدید در مواد مختلف فاز برگشت پذیر
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A chromatographic and thermodynamic study of the derivatives of 4,5-disubstituted-2,4-dihydro-3H-1,2,4-triazole-3-thiones (and their Mannich bases) was undertaken. Three reversed-phase materials: a Zorbax Extend-C18, Cogent UDC Cholesterol and Regis IAM. PC. DD. 2 were studied. Plots of log k vs. the volume fraction of organic solvent in the mobile phase (φ) and the van't Hoff relationships were constructed. The van't Hoff plots revealed at least one phase transition on Cogent UDC Cholesterol and Regis IAM. PC. DD. 2. Obtained results indicated that adsorption was enthalpy-entropy driven. Cholesterol phase and Regis IAM. PC. DD. 2 in contrast to conventional octadecyl silica phase at aqueous-organic mobile phase demonstrated some liquid crystals behavior at defined conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1338, 18 April 2014, Pages 188-196
نویسندگان
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