کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7613735 1493597 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simultaneous determination of oxathiapiprolin and two metabolites in fruits, vegetables and cereal using a modified quick, easy, cheap, effective, rugged, and safe method and liquid chromatography coupled to tandem mass spectrometry
ترجمه فارسی عنوان
اندازه گیری همزمان اکساسیاپیپرولین و دو متابولیت در میوه ها، سبزیجات و غلات با استفاده از یک روش اصلاح سریع، آسان، ارزان، موثر، ناهموار و ایمن و کروماتوگرافی مایع همراه با طیف سنجی جرمی دو طرفه
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
An effective and rapid analytical method for the simultaneous determination of a new fungicide oxathiapiprolin and its metabolites (IN-E8S72 and IN-WR791) residues in fruits (grape, watermelon, watermelon peel), vegetables (cucumber, tomato, potato) and cereal (wheat) was developed by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) using the modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction concept. Three target compounds were extracted from all matrices with 1% (V/V) formic acid aqueous solution and acetonitrile then cleaned by dispersive solid phase extraction (dSPE) with octadecylsilane (C18) and graphitized carbon black (GCB). The determination of the target compounds was achieved within a 5.1 min run time by using an UPLC HSS T3 column connected to an electrospray ionization source (ESI, positive ion mode) for oxathiapiprolin and the negative mode for the two metabolites. The method showed excellent linearity (R2 > 0.9904) for target compounds. The limit of detection (LOD) for the three compounds ranged from 0.5 μg kg−1 to 7.5 μg kg−1 and the limits of quantitation (LOQ) were 1 μg kg−1 and 10 μg kg−1 for oxathiapiprolin and the metabolites, respectively. The mean recoveries from seven matrices ranged from 81.5 to 110.7%, with intra-day relative standard deviations (RSDr) in the range of 0.8-12.0% for all three test compounds. The inter-day RSDR were less than 14.5% for all of the recovery tests. The method was successfully applied for simultaneous analysis of oxathiapiprolin and its metabolites in actual trial samples, indicating its effectiveness in investigating oxathiapiprolin and its metabolites in the food.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1329, 14 February 2014, Pages 30-37
نویسندگان
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