کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7622361 1494524 2018 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mushroom polysaccharides from Ganoderma lucidum and Poria cocos reveal prebiotic functions
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Mushroom polysaccharides from Ganoderma lucidum and Poria cocos reveal prebiotic functions
چکیده انگلیسی
Ganoderma lucidum and Poria cocos are the medicinal mushrooms that have been used as traditional Chinese medicines and consumed as functional foods. We hypothesized that these mushroom polysaccharides could contribute to health benefits, in part, by modulating gut microbiota (GM). In this study, mushroom polysaccharides derived from fruiting bodies and mycelia were administrated daily (750 mg/kg) to 6 weeks-old C57BL/6J mice for 15 days. Then, mice GM was evaluated using ERIC-PCR and 16S amplicon sequencing. A total of 2.59 million high-quality reads (>200 bp) were processed and evaluated for GM profiling. Polysaccharides reduced OTUs diversity and significantly (p < .01) remodeled GM compositions. Bacteria that have been reported for anti-obesity, SCFA-producer, polysaccharides/xylan degradation, and lactic acid production were significantly (p < .05) abundant in mice treated with polysaccharides. We conclude that these polysaccharides act as prebiotics to modulate GM composition thereby potentially contribute to the health promotion effects of G. lucidum and P. cocos.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 41, February 2018, Pages 191-201
نویسندگان
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