کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7623094 | 1494544 | 2016 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A metabolomics approach to identify factors influencing their activity relative to oleanolic acid contents in Korean mistletoe types
ترجمه فارسی عنوان
یک روش متابولیکی برای شناسایی عوامل موثر بر فعالیت آنها نسبت به محتوای الیانول اسید در گونه های آسیایی کره ای
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
The metabolite changes in Korean mistletoe, as functional food, and their effects on its biological activity were monitored. The Korean mistletoe species were successfully distinguished by hierarchical clustering analysis (HCA) in atmospheric-pressure chemical ionization (APCI) and electrospray ionization (ESI) mode. As shown by the PCA scatter plot and loading plot, the Santalaceae family exhibited significant markers derived from oleanolic acid, whereas the Loranthaceae family exhibited tentative markers derived from glycosidic derivatives of quercetin and kaempferol. The mistletoe extracts also inhibited plasminogen activator inhibitor 1 (PAI-1) differently depending on the mistletoe family. The Santalaceae family was shown to be a potent inhibitor of PAI-1, with an IC50 value of around 40.0âµg/mL. In contrast, the Loranthaceae family extracts did not inhibit PAI-1. Importantly, discrimination was shown across the chemotaxonomy of the plant, which correlated strongly with the oleanolic acid contents in Korean mistletoe.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 22, April 2016, Pages 64-72
Journal: Journal of Functional Foods - Volume 22, April 2016, Pages 64-72
نویسندگان
Hyuk-Hwan Song, Hyung Won Ryu, Hui-Seong Kim, Chan-Soo Kim, Hwa-Ja Hyun, Hyeong-Kyu Lee, Sei-Ryang Oh,