DHA-PC and DHA-PS improved Aβ1-40 induced cognitive deficiency uncoupled with an increase in brain DHA in rats

- DHA-PS has more significant effect on Aβ-induced cognitive deficiency than DHA-PC.
- .DHA-PLs improved Aβ-induced brain dysfunction uncoupled with brain DHA increase.
- The mechanism of DHA-PLs involved in ameliorating Aβ induced oxidative stress, inflammation cascade and Tau pathology.
- The effect of DHA-PLs on Aβ-induced cognitive deficiency is closely related with the polar group of phospholipid.