کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7624619 | 1494553 | 2014 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prebiotic effects of cassava bagasse in TNO's in vitro model of the colon in lean versus obese microbiota
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کلمات کلیدی
GLP-1Netherlands Organization for Applied Scientific ResearchTim-2SIEMTNOBCFAPYYFOSGOSSCFALPSbranched-chain fatty acids - اسیدهای چرب زنجیره ایShort-chain fatty acids - اسیدهای چرب کوتاه مدتIn vitro - درونکشتگاهیFructooligosaccharides - فروکتولیکساکارید هاCassava bagasse - قارچ کاساواlipopolysaccharide - لیپوپلی ساکاریدObesity - مرض چاقیGut microbiota - میکروبی خوب استprebiotic - پروبیوتیکpeptide YY - پپتید YYglucagon-like peptide 1 - پپتید مشابه گلوکاگون 1
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Prebiotic effects of cassava bagasse in TNO's in vitro model of the colon in lean versus obese microbiota Prebiotic effects of cassava bagasse in TNO's in vitro model of the colon in lean versus obese microbiota](/preview/png/7624619.png)
چکیده انگلیسی
Obesity is currently a worldwide epidemic that has serious consequences for health. It has been suggested that the gut microbiota can influence body weight, e.g., by producing short-chain fatty acids (SCFA), which are substrates for the host and induce the release of satiety hormones (e.g., PYY). To test the potential prebiotic effect of cassava bagasse (a by-product from cassava flour and starch production) in vitro fermentation experiments were performed using fecal microbiota originating from lean and obese subjects in a validated model of the colon (TIM-2). The microbial composition and production of microbial metabolites were analysed. Cassava was found to modulate the microbiota composition, since it stimulated the growth of the genera Bifidobacterium and Roseburia. The production of SCFA was similar to that for inulin (positive control). Although supplementary in vivo studies with cassava bagasse are needed, this study shows for the first time the prebiotic potential of cassava bagasse.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 11, November 2014, Pages 210-220
Journal: Journal of Functional Foods - Volume 11, November 2014, Pages 210-220
نویسندگان
C. Bussolo de Souza, G. Roeselers, F. Troost, D. Jonkers, M.E. Koenen, K. Venema,